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Dynamic study on anti-collapse design for underground structures subjected to explosion

Yang Liming,Zhou Fenghua,Dong Xinlong,Wang Lili

Strategic Study of CAE 2011, Volume 13, Issue 3,   Pages 29-37

Abstract: How to reduce the strength of tensile stress wave is a key problem for underground protective structureFormulations, that are often used currently to describe the minimum deepness of underground protectivestructure against spalling collapse, were deduced based on many assumptions for simplification.The experimental results show that the anti-collapse capability of an underground structure with highanti-collapse strength of underground protective structures subjected to explosive loading.

Keywords： underground protective structure     concrete tensile properties     anti-collapse     stress waves    

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Waterproofing Technology for Underground Fabricated Structure Joints Based on the Open Cut Method

Huang Mingli,Yang Ze,Tan Zhongsheng and Wang Wenzheng

Strategic Study of CAE 2017, Volume 19, Issue 6,   Pages 131-139 doi: 10.15302/J-SSCAE-2017.06.019

Abstract: However, the use of underground fabricated structures in China has only recently begun.Owing to the complexity of the underground environment, waterproofing underground fabricated structureIn this paper, based on an analysis of the joints of an underground fabricated building and of the currenttechnology, we propose the use of an epoxy grouting material, which is used to pot the prefabricated structurefoundation pit, and expound the effect of the prefabricated solidified soil on the waterproofing of the underground

Keywords： prefabricated structures     underground structure joint     epoxy grouting material     prefabricated solidified    

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An end-to-end 3d seismic simulation of underground structures due to point dislocation source by using

Zhenning BA; Jisai FU; Zhihui ZHU; Hao ZHONG

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 12,   Pages 1515-1529 doi: 10.1007/s11709-022-0887-0

Abstract: of this approach is that it realizes the entire process simulation from point dislocation source to undergroundstructure.This approach can provide an effective solution for seismic analysis of underground structures underTaking Daikai subway station as an example, the seismic response of the underground structure is simulatedunderground structure is 96.5% and the change of source parameters can lead to the change of structural

Keywords： source-to-structure simulation     FK-FEM hybrid approach     underground structures     point dislocation source    

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Engineering philosophical thinking of the old mining area transformation development

Jin Zhixin

Strategic Study of CAE 2014, Volume 16, Issue 10,   Pages 64-70

Abstract:

The transformation development of the old mining area is a complex system engineering, it needs to command the overall situation by standing on the height of system engineering and needs to follow the harmonization in engineering, nature, science, technology, industry, economy and society. Engineering innovation is the main part of the technology innovations, it pushes the development of scientific, technical, industrial, economic and social, also the engineering innovation is relied on scientific and technological progress. Ecological protection is the premise of engineering development, and the ecological engineering construction is promoted by economic development. The protecting and mining of rare coking coal resources is a unity of oppisites. The companies of producting coking coal must pursue both immediate and long-term interests, especially the old mining, so the company should resolve the conflict between the scarcity of resources and the growth of demands by implementing limited exploitation, increasing resource recovery and efficiently recycling of coking coal resources to build the big-vertical-deep industry group. The conflict between frequent accidents and high input of existing security control promotes the development of security theory and technology, the transformation of security theory and technology from system security to structural security is a inevitable process of development.

Keywords： engineering philosophical     asymmetric development     green migration     big-vertical-deep industry group     protectivemining     security structure theory    

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Enhancing thermostability of -mannanase by protective additives

LIU Zhaohui, QI Wei, WU Weina, LIU Yue, HE Zhimin

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 4,   Pages 439-442 doi: 10.1007/s11705-008-0062-8

Abstract: sugars (glucose, mannose, fructose, sucrose and chitosan) and polyols (glycol, glycerol and sorbitol) as protectiveMeanwhile, the protective mechanism of the additives against deactivation of enzyme was also discussed

Keywords： protective additive     g/L     orthogonal experimental     combination additive     corresponding    

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Protective effects of lignin fractions obtained from grape seeds against bisphenol AF neurotoxicity via

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 7,   Pages 976-989 doi: 10.1007/s11705-022-2237-0

Abstract: An immunofluorescence assay demonstrated that grape seed lignin induced protective effects on BPAF-injured

Keywords： grape seed lignin     structure     antioxidant     NE-4C cells     neuroprotection    

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Intelligent Monitoring System Based on Spatio–Temporal Data for Underground Space Infrastructure Review

Bowen Du, Junchen Ye, Hehua Zhu, Leilei Sun, Yanliang Du

Engineering 2023, Volume 25, Issue 6,   Pages 194-203 doi: 10.1016/j.eng.2022.07.016

Abstract: The advancement of underground space utilization has led to the development of three characteristicsHowever, compared to buildings and bridges overground, the diseases and degradation that occur underground

Keywords： Structure health monitoring     Underground space infrastructure     Machine learning     Spatio–temporal data    

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The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 8-14 doi: 10.1007/s11684-011-0109-y

Abstract: influence of brain death on the viability of donor livers and to summarize the mechanisms of the different protective

Keywords： brain death     donor liver    

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PAK1 is a novel cardiac protective signaling molecule

Yunbo Ke,Xin Wang,Xu Yu Jin,R. John Solaro,Ming Lei

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 399-403 doi: 10.1007/s11684-014-0380-9

Abstract:

We review here the novel cardiac protective effects of the multifunctional enzyme, p21-activated kinaseassemble an overview of the recent findings on PAK1 signaling in the heart, particularly its cardiac protectiveWe discuss the anti-adrenergic and antihypertrophic cardiac protective effects of PAK1, as well as its

Keywords： p21-activated kinase 1 (PAK1)     heart    

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Antioxidative potential of metformin: Possible protective mechanism against generating OH radicals

Huibin Guo, Ning Wang, Xiang Li

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 2, doi: 10.1007/s11783-020-1313-2

Abstract: Abstract • Metformin consumes O2−• and OH• induced by PM are proposed. • OH• dominated the oxidation of metformin compared with O2−• • Metformin can prevent the harm of ROS induced by PM to human health. • Antioxidative potential of metformin was first proposed to provide measures. Exposure to particulate matter (PM) can lead to the excessive accumulation of reactive oxygen species (ROS), which causes oxidative stress and endangers human health. In this study, the effects of metformin on PM-induced radicals were investigated, and the antioxidation reaction mechanism of metformin was analyzed by the density functional theory (DFT) method. The corresponding results revealed that the consumption rate of dithiothreitol (DTT) increased as the metformin concentration (0–40 mmol/L) increased under exposure to PM active components. Moreover, the OH radical content decreased as the metformin concentration increased. This result may be related to the consumption of PM-induced OH radicals by metformin, which promotes the DTT consumption rate. Additionally, because the initiation reaction has a high barrier, the oxidation reaction rate between metformin and •O2− is not very fast, although various catalysts may be present in the human environment. Importantly, we found that the barrier of metformin induced by OH radicals is only 9.6 kcal/mol while the barrier of metformin induced by oxygen is 57.9 kcal/mol, which shows that the rate of the •OH-initiated oxidative reaction of metformin is much faster and that this reaction path occurs more easily. By sample analysis, the mean OH radical generation was 55 nmol/min/g (ranging from 5 to 105 nmol/min/g) on haze days and 30 nmol/min/g (ranging from 10 to 50 nmol/min/g) on non-haze days. Moreover, OH radical generation was higher on haze days than on neighboring non-haze days. Taken together, all data suggest that metformin could consume the PM-induced radicals, such as OH radicals and •O2−, thereby providing health protection.

Keywords： Antioxidative potential     Metformin     Mechanism     OH radical     Health protection.    

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Nano-copper ions assembled cellulose-based composite with antibacterial activity for biodegradable personal protective

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1544-1554 doi: 10.1007/s11705-022-2288-2

Abstract: The current SARS-CoV-2 pandemic has resulted in the widespread use of personal protective equipment,transmission, resource consumption, and environmental impact of waste, while also expanding the range of protective

Keywords： cellulose-based     nanocomposite     biodegradable antibacterial fabric     nano-copper ions     face masks    

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Effect of hyperlipidemia on endothelial VCAM-1 expression and the protective role of fenofibrate

WU Jun, LIN Jinchao, HE Zhaochu, OU Biru, GUO Haisen

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 356-358 doi: 10.1007/s11684-007-0068-5

Abstract: The effect of hyperlipidemia and inflammation on endothelial functions was studied. The enrolled included control (basic chow), hyperlipidemia and fenofibrate-treated groups (high fat diet). The hyperlipidemia model was set up by four-week atherogenic diet, followed by a 16-week treatment in the fenofibrate-treated group (fenofibrate 40 mg/kg every day) and without treatment in the hyperlipidemia group, respectively. In the 20th week, serum lipid level and NO levels were measured, and the expression of vascular cell adhesion molecule-1 (VCAM-1) and cell adhesiveness in aortic endothelia observed by computer-aided system. Compared with the control group, hyperlipidemia rats showed lower levels of NO and ncreases in leukocyte accumulation on the endothelial surface, also stronger and more extensive endothelial expression of VCAM-1. In fenofibrate-treated group, the expression of VCAM-1 and leukocyte accumulation on the endothelial surface was decreased, while serum levels of NO were increased as compared with hyperli pidemia group. Hyperlipidemia can inhibit the NO activity and promote the damage of VACA-1 to aortic endothelia. Fenofibrate can effectively prevent the pathogenesis of atherosclerosis by restoring NO levels and down-regulating the VCAM-1 expression.

Keywords： endothelial     16-week treatment     leukocyte accumulation     mg/kg     NO    

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Immunogenicity and protective immunity against otitis media caused by pneumococcus in mice of Hib conjugate

Zeyu Chen,Rong Guo,Jianghong Xu,Chuangjun Qiu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 490-498 doi: 10.1007/s11684-016-0470-y

Abstract:

This study evaluated the immunogenicity and protective immunity of a Hemophilus influenzaeelimination rate of pneumococcus and the inflammation of the middle ear showed the effectiveness of protective

Keywords： conjugate vaccine     pneumococcal surface adhesin A     Hemophilus influenzae b     immunogenicity     otitis media    

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PROTECTIVE ROLES OF D1 PROTEIN TURNOVER AND THE XANTHOPHYLL CYCLE IN TOMATO (

Tao LU, Jiazhi LU, Mingfang QI, Zhouping SUN, Yufeng LIU, Tianlai LI

Frontiers of Agricultural Science and Engineering   Pages 262-279 doi: 10.15302/J-FASE-2021383

Abstract: D1 protein turnover and the xanthophyll cycle (XC) are important photoprotective mechanisms in plants that operate under adverse conditions. Here, streptomycin sulfate (SM) and dithiothreitol (DTT) were used in tomato plants as inhibitors of D1 protein turnover and XC to elucidate their photoprotective impacts under sub-high temperature and high light conditions (HH, 35°C, 1000 µmol·m ·s ). SM and DTT treatments significantly reduced the net photosynthetic rate, apparent quantum efficiency, maximum photochemical efficiency, and potential activity of photosystem II, leading to photoinhibition and a decline in plant biomass under HH. The increase in reactive oxygen species levels resulted in thylakoid membrane lipid peroxidation. In addition, there were increased non-photochemical quenching and decreased chlorophyll pigments in SM and DTT application, causing an inhibition of D1 protein production at both transcriptional and translational levels. Overall, inhibition of D1 turnover caused greater photoinhibition than XC inhibition. Additionally, the recovery levels of most photosynthesis indicators in DTT-treated plants were higher than in SM-treated plants. These findings support the view that D1 turnover has a more important role than XC in photoprotection in tomato under HH conditions.

Keywords： D1 turnover     photoinhibition     photoprotection     photosynthesis     tomato     xanthophyll cycle    

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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract: However, its protective abilities against I/R injury in the liver are unknown.Our data suggested that GLP-2 pretreatment may have a protective effect on liver I/R injury.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Title Author Date Type Operation

Dynamic study on anti-collapse design for underground structures subjected to explosion

Yang Liming,Zhou Fenghua,Dong Xinlong,Wang Lili

Journal Article

Waterproofing Technology for Underground Fabricated Structure Joints Based on the Open Cut Method

Huang Mingli,Yang Ze,Tan Zhongsheng and Wang Wenzheng

Journal Article

An end-to-end 3d seismic simulation of underground structures due to point dislocation source by using

Zhenning BA; Jisai FU; Zhihui ZHU; Hao ZHONG

Journal Article

Engineering philosophical thinking of the old mining area transformation development

Jin Zhixin

Journal Article

Enhancing thermostability of -mannanase by protective additives

LIU Zhaohui, QI Wei, WU Weina, LIU Yue, HE Zhimin

Journal Article

Protective effects of lignin fractions obtained from grape seeds against bisphenol AF neurotoxicity via

Journal Article

Intelligent Monitoring System Based on Spatio–Temporal Data for Underground Space Infrastructure

Bowen Du, Junchen Ye, Hehua Zhu, Leilei Sun, Yanliang Du

Journal Article

The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Journal Article

PAK1 is a novel cardiac protective signaling molecule

Yunbo Ke,Xin Wang,Xu Yu Jin,R. John Solaro,Ming Lei

Journal Article

Antioxidative potential of metformin: Possible protective mechanism against generating OH radicals

Huibin Guo, Ning Wang, Xiang Li

Journal Article

Nano-copper ions assembled cellulose-based composite with antibacterial activity for biodegradable personal protective

Journal Article

Effect of hyperlipidemia on endothelial VCAM-1 expression and the protective role of fenofibrate

WU Jun, LIN Jinchao, HE Zhaochu, OU Biru, GUO Haisen

Journal Article

Immunogenicity and protective immunity against otitis media caused by pneumococcus in mice of Hib conjugate

Zeyu Chen,Rong Guo,Jianghong Xu,Chuangjun Qiu

Journal Article

PROTECTIVE ROLES OF D1 PROTEIN TURNOVER AND THE XANTHOPHYLL CYCLE IN TOMATO (

Tao LU, Jiazhi LU, Mingfang QI, Zhouping SUN, Yufeng LIU, Tianlai LI

Journal Article

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article